Synthesis and Characterization of Homo and Mixed Ligand Complexes of Fe(III) with Hydroxypyridinone and Hydroxypyranone Type Ligands

Mixed Ligand Complexes of Fe(III)

Authors

  • Kanwal Zahid Department of Chemistry, University of Karachi, Karachi-75270, Pakistan
  • Shazia Nisar Department of Chemistry, University of Karachi, Karachi-75270, Pakistan
  • Saima Imad Chemical Metrology Division, National Physical and Standards Laboratory (PCSIR), Islamabad, Pakistan
  • Shazia Perveen Department of Chemistry, NED University of Engineering and Technology, Karachi-75270, Pakistan
  • Shazia Ghaffar Department of Chemistry, University of Karachi, Karachi-75270, Pakistan
  • Nasreen Fatima Department of Chemistry, University of Karachi, Karachi-75270, Pakistan

DOI:

https://doi.org/10.52763/PJSIR.PHYS.SCI.63.1.2020.12.17

Keywords:

mixed ligand complexes, iron, hydroxypyridinone, hydroxypyranone, chelation therapy

Abstract

 

Hydroxypyridinone and hydroxypyranone are known to be used for the treatment of iron overload by chelation therapy for a long time. Both the ligands have their own side effects when used as medicines. In the present study homo and mixed ligand complexes of both the ligands with iron were prepared and characterized by UV-visible spectrophotometry, Potentiometric study, IR spectroscopy, SEM/EDX and XRD. Overlay spectra obtained from UV-visible spectroscopy of our studied system show the formation of different types of species and confirm that mixed ligand complex is different from the other two systems. Potentiometric titration curves of homo and mixed ligand complexes show the formation of different types of species at different pH and confirm the formation of mixed ligand complex. The comparative results of SEM images of these systems show different surface topologies and hence conform to the formation of mixed ligand complex.

 

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Published

2020-03-18

How to Cite

Zahid, K., Nisar, S., Imad, S., Perveen, S., Ghaffar, S., & Fatima, N. (2020). Synthesis and Characterization of Homo and Mixed Ligand Complexes of Fe(III) with Hydroxypyridinone and Hydroxypyranone Type Ligands: Mixed Ligand Complexes of Fe(III). Pakistan Journal of Scientific & Industrial Research Series A: Physical Sciences, 63(1), 12–17. https://doi.org/10.52763/PJSIR.PHYS.SCI.63.1.2020.12.17